Amyloidosis is a rare metabolic disease with plenty of complications in the cardiovascular, kidneys, and gastrointestinal systems. One of the tell-tale signs of amyloidosis is a build-up of the amyloid protein in different tissues throughout the body. This protein shouldn’t be there, and your body is not prepared to handle this substance.
1This can lead to several symptoms, some of which are listed below:
Enlargement and hardening of the liver
This is often one of the first signs of amyloidosis. The liver is one of the organs most affected by the build-up of amyloid protein. This organ clears the blood from toxins and foreign substances. It receives amyloid proteins and recognizes this substance as something that should not exist. But the liver doesn’t have an enzyme to break down amyloid, and it accumulates and causes hepatomegaly. An enlarged liver is sometimes painful as well.